Mitochondrial dysfunction in liver failure requiring transplantation

Cardiac Failure after Liver Transplantation Requiring a Biventricular Assist Device

Increased hepatic iron load in extrahepatic organs of cirrhotic patients with and without hereditary hemochromatosis portends a poorer long term prognosis after liver transplant. Hepatic as well as nonhepatic iron overload is associated with increased infectious and postoperative complications, including cardiac dysfunction. In this case report, we describe a cirrhotic patient with alpha 1 anti...

Mitochondrial dysfunction in heart failure.

angina was reached. Angina, unfortunately, is a subjective measure. Irrespective of how “objective” the investigators were in determining the success or failure of antianginal therapy, the use of a subjective end point may have inadvertently introduced bias into the trial. It is difficult to draw proper conclusions from such a trial when large crossover rates are allowed. With respect to the Eu...

Dialysis in liver failure and liver transplantation.

[Liver transplantation in acute liver failure].

Acute hepatic failure is characterized by jaundice and hepatic encephalopathy within eight weeks after the onset of disease. Although acute hepatic failure is a rare occurrence, its rapid progression and high mortality (50 to 90%, depending on the etiology of disease) necessitate immediate intervention. In the absence of causal therapy, orthotopic liver transplantation is currently the only def...

Renal Dysfunction and Liver Transplantation

Liver transplantation, whether living donor (LDLT) or deceased donor (DDLT), is currently the treatment of choice for patients with advanced liver disease. While initially the focus was on acceptable short-term survival, currently the efforts are aimed at improving longterm prognosis. Thus, focus is now on the quality of life after liver transplantation, as well as prediction and management of ...